Factors Influencing Cerebral Blood Flow and Metabolism

Factors influencing cerebral blood flow and metabolism; a review.

Factors Influencing Cerebral Blood Flow

The results of studies utilizing the nitrous oxide technic for measuring cerebral blood flow have been reviewed and divided into three groups: (1) those in which cerebral blood flow and metabolism were normal, (2) those in which cerebral blood flow was increased, and (3) those in which cerebral blood flow and metabolism were decreased. The factors which apparently regulate and control cerebral ...

Cerebral Blood Flow Physiology and Metabolism

The brain comprises only 2% of total body weight; however, under normal conditions, it receives 15–20% of the cardiac output and accounts for 20% of total body oxygen consumption. Because energy reserves within the brain are negligible, adequate blood flow is essential for the provision of a continuous supply of energy-producing substrates and for the removal of the byproducts of cellular metab...

5 Brain metabolism and cerebral blood flow

Cerebral blood flow is influenced and regulated by a number of factors, including arterial blood pressure, intracranial pressure, venous outflow, blood viscosity, PaCO2 and PaO2, collateral flow, vasoreactivity and the status of cerebral autoregulation. The regulation of vascular resistance lies mainly in the arterioles and precapillary segments (Auer and Loew, 1983). It is important to note th...

Cerebral blood flow and metabolism during exercise.

During exercise regional cerebral blood flow (rCBF), as blood velocity in major cerebral arteries and also blood flow in the internal carotid artery increase, suggesting an increase in blood flow to a large part of the brain. Such an increase in CBF is independent of the concomitant increase in blood pressure but is modified by the alteration in arterial carbon dioxide tension (PaCO(2)). Also, ...